The MeDiTATe Winter School: “Big Data Analytics, from engineering to clinical”
Fondazione Toscana G. Monasterio will host the MeDiTATe Winter School: “Big Data Analytics, from engineering to clinical” from February 20th to 24th, 2023.
Our Early Stage Researchers will have the opportunity to follow several lessons, with different topics within the event’s five days:
- Day 1: Clinics and biology session
- Day 2: From clinics to engineering
- Day 3: Advanced 3D printing;
- Day 4 & Day 5: Artificial Intelligence.
This Winter School will also include two specific training events scheduled in the MeDiTATe program:
- Training event 4 by GE Healthcare: Magnetic Resonance acquisition and analysis;
- Training event 10 by NADIR: Advanced Polymer manufacturing.
“An image-based approach for the estimation of arterial local stiffness in vivo”, a new paper in collaboration with the MeDiTATe project
A new paper An image-based approach for the estimation of arterial local stiffness in vivo has been published in the Frontiers in Bioengineering and Biotechnology journal in collaboration with the MeDiTATe project.
The paper was written by Simona Celi, Emanuele Gasparotti, Katia Capellini and Emanuele Vignali from BioCardioLab (Fondazione Toscana G. Monasterio), Francesco Bardi (ESR 10), Martino Andrea Scarpolini (ESR 09), Carlo Cavaliere (IRCCS SynLab SDN) e Filippo Cademartiri (Dipartimento Immagini, Fondazione Toscana Gabriele Monasterio).
Here follows the paper’s abstract:
The analysis of mechanobiology of arterial tissues remains an important topic of research for cardiovascular pathologies evaluation. In the current state of the art, the gold standard to characterize the tissue mechanical behavior is represented by experimental tests, requiring the harvesting of ex-vivo specimens. In recent years though, image-based techniques for the in vivo estimation of arterial tissue stiffness were presented. The aim of this study is to define a new approach to provide local distribution of arterial stiffness, estimated as the linearized Young’s Modulus, based on the knowledge of in vivo patient-specific imaging data. In particular, the strain and stress are estimated with sectional contour length ratios and a Laplace hypothesis/inverse engineering approach, respectively, and then used to calculate the Young’s Modulus. After describing the method, this was validated by using a set of Finite Element simulations as input. In particular, idealized cylinder and elbow shapes plus a single patient-specific geometry were simulated. Different stiffness distributions were tested for the simulated patient-specific case. After the validation from Finite Element data, the method was then applied to patient-specific ECG-gated Computed Tomography data by also introducing a mesh morphing approach to map the aortic surface along the cardiac phases. The validation process revealed satisfactory results. In the simulated patient-specific case, root mean square percentage errors below 10% for the homogeneous distribution and below 20% for proximal/distal distribution of stiffness. The method was then successfully used on the three ECG-gated patient-specific cases. The resulting distributions of stiffness exhibited significant heterogeneity, nevertheless the resulting Young’s moduli were always contained within the 1–3 MPa range, which is in line with literature.
Polymeric heart valve replacements workshop recording is now available on the University of Sydney website
Last September 2022, the University of Sydney, one of the partners of the MeDiTATe project, hosted a workshop on heart valve replacements.
Prof. Marco Evangelos Biancolini, Principal Investigator of the MeDiTATe project, was one of the international guests, giving a speech on Digital Twins & Medicine 4.0.
Full recording of the speech is now available on the University of Sydney website, at the following link.
“Fabrication of Compliant and Transparent Hollow Cerebral Vascular Phantoms for In Vitro Studies Using 3D Printing and Spin–Dip Coating”, the latest publication of the MeDiTATe project, now available in Materials journal by MDPI
Beatrice Bisighini, ESR 03 of the MeDiTATe project, published the paper Fabrication of Compliant and Transparent Hollow Cerebral Vascular Phantoms for In Vitro Studies Using 3D Printing and Spin–Dip Coating in the Materials journal by MDPI.
The paper, developed in collaboration with Pierluigi Di Giovanni (HSL), Alba Scerrati (University of Ferrara), Federica Trovalusci and Silvia Vesco (University of Rome “Tor Vergata”), is available on the MDPI website at this link.
Here follows the publication’s abstract. Read More
A new MeDiTATe project publication: “Potential of auxetic designs in endovascular aortic repair: A computational study of their mechanical performance”
Rahul Sathish Vellaparambil, ESR 08 of the MeDiTATe project, published the paper titled Potential of auxetic designs in endovascular aortic repair: A computational study of their mechanical performance in the Journal of the Mechanical Behavior of Biomedical Materials.
The work was developed in collaboration with Woo-Suck Han and Stéphane Avril from Mines Saint-Étienne and Pierluigi Di Giovanni from the R&D department of HSL.
The paper, whose abstract is reported in the following lines, Read More
MeDiTATe Newsletter #1 – December 2022
The first MeDiTATe project newsletter is out! It contains main news, latest events and much more of the activities carried out in the last months of 2022.
The newsletter can be downloaded at the following link. MeDiTATe Newsletter #1 December 2022
New section “Steering Committee” for the MeDiTATe website
A new section is available on the MeDiTATe project website. It is now possible to visit the Steering Committee area where members’ roles in terms of project responsibilities, ESRs supervision and academic and research background are explained in detail.
The Steering Committee includes: Read More
International workshop: “Biomathematics and mechanics in cardiovascular medicine” at Mines Saint-Étienne
The Centre for Biomedical and Healthcare Engineering at Mines Saint-Étienne will host the international workshop “Biomathematics and mechanics in cardiovascular medicine” next December 7th, 2022.
The workshop will present new trends in blood circulation modelling, blood flows numerical simulations and biological tissues mechanical properties.
Stéphane Avril, Research Coordinator of the MeDiTATe project, is one of the organizers and speakers of the event, while Beatrice Bisighini (ESR 03) will be presenting her work “Machine learning and reduced order modelling for the real-time simulation of flow diverters deployment”.
For more details or to follow the workshop online visit the event webpage or contact Stephane Avril on LinkedIn.
Recent Posts
- Leonardo Geronzi ESR 02 of the MeDiTATe Project among Forbes Italia’s Top 100 Under 30
- Monica Emendi successfully defended her PhD thesis defense
- Martino Andrea Scarpolini successfully defended his PhD thesis defense
- Eirini Kardampiki successfully defended her PhD thesis defense
- MeDiTATe Newsletter #4 – December 2023
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