MeDiTATe (“the Medical Digital Twin for Aneurysm Prevention and Treatment”) will deliver a comprehensive framework of simulation and imaging technologies, targeted at industrial and clinical-translation to accelerate the process of personalised cardiovascular medical procedure, validated through an integrated experimental programme to ultimately improve patient care.

The core idea of MeDiTATe is therefore to develop a Digital Twin and to make it available as “a service” for all in academia, hospital and industry.

In particular, the project aims at:

  • translating the well-known expertise specific of “traditional” engineering into a real clinical environment;
  • ensuring the collaboration between research/academic organizations with industries to investigate cutting-edge issues for Research & Development in the aneurysms prevention and treatment by means of Digital Twin approach;
  • providing 14 Early Stage Researchers with an enviable skills mix, making them attractive to both academia and industry, preparing them for a competitive employment market and individually balancing technical and complementary skills training.

To achieve those goals, the following techniques are integrated in MeDiTATe:

  • clinical and imaging data;
  • Computer-aided Engineering (CAE) multi-physics simulation with Radial Basis Functions (RBFs) mesh morphing, Finite Element Method (FEM), Computational Fluid Dynamics (CFD), Fluid-Structure Interaction (FSI), inverse FEM;
  • Real time interaction with the Digital Twin by Augmented Reality, Haptic Devices and Reduced Order Models (ROM);
  • High Performance Computing (HPC tools, including Graphic Processing Units (GPUs)), and cloud-based paradigms for fast and automated CAE processing of clinical database;
  • Big Data management for population of patients imaging data and high-fidelity CAE twins;
  • Additive Manufacturing of physical mock-up for surgical planning and training.

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