“Fabrication of Compliant and Transparent Hollow Cerebral Vascular Phantoms for In Vitro Studies Using 3D Printing and Spin–Dip Coating”, the latest publication of the MeDiTATe project, now available in Materials journal by MDPI

Beatrice Bisighini, ESR 03 of the MeDiTATe project, published the paper Fabrication of Compliant and Transparent Hollow Cerebral Vascular Phantoms for In Vitro Studies Using 3D Printing and Spin–Dip Coating in the Materials journal by MDPI.
The paper, developed in collaboration with Pierluigi Di Giovanni (HSL), Alba Scerrati (University of Ferrara), Federica Trovalusci and Silvia Vesco (University of Rome “Tor Vergata”), is available on the MDPI website at this link.
Here follows the publication’s abstract. Read More
A new MeDiTATe project publication: “Potential of auxetic designs in endovascular aortic repair: A computational study of their mechanical performance”

Rahul Sathish Vellaparambil, ESR 08 of the MeDiTATe project, published the paper titled Potential of auxetic designs in endovascular aortic repair: A computational study of their mechanical performance in the Journal of the Mechanical Behavior of Biomedical Materials.
The work was developed in collaboration with Woo-Suck Han and Stéphane Avril from Mines Saint-Étienne and Pierluigi Di Giovanni from the R&D department of HSL.
The paper, whose abstract is reported in the following lines, Read More
MeDiTATe Newsletter #1 – December 2022

The first MeDiTATe project newsletter is out! It contains main news, latest events and much more of the activities carried out in the last months of 2022.
The newsletter can be downloaded at the following link. MeDiTATe Newsletter #1 December 2022
New section “Steering Committee” for the MeDiTATe website

A new section is available on the MeDiTATe project website. It is now possible to visit the Steering Committee area where members’ roles in terms of project responsibilities, ESRs supervision and academic and research background are explained in detail.
The Steering Committee includes: Read More
International workshop: “Biomathematics and mechanics in cardiovascular medicine” at Mines Saint-Étienne

The Centre for Biomedical and Healthcare Engineering at Mines Saint-Étienne will host the international workshop “Biomathematics and mechanics in cardiovascular medicine” next December 7th, 2022.
The workshop will present new trends in blood circulation modelling, blood flows numerical simulations and biological tissues mechanical properties.
Stéphane Avril, Research Coordinator of the MeDiTATe project, is one of the organizers and speakers of the event, while Beatrice Bisighini (ESR 03) will be presenting her work “Machine learning and reduced order modelling for the real-time simulation of flow diverters deployment”.
For more details or to follow the workshop online visit the event webpage or contact Stephane Avril on LinkedIn.
An interview with Dr. Emiliano Costa, Communication, Dissemination and Exploitation Coordinator of the MeDiTATe project

We had a talk with Dr. Emiliano Costa, a member of the Supervisory Board of the MeDiTATe project and Principal Engineer at RINA. During his 15+ years of experience, he participated in both Italian and European co-funded research projects mainly in coordination and simulation-based tasks. In MeDiTATe he has a three-fold role: Scientist-in-Charge of RINA, Industrial Supervisor of ESR 07 and ESR 12 and Communication, Dissemination and Exploitation Coordinator.
What about RINA’s experience in MSCA projects? Do you think it is important for large companies to be involved in EU-financed projects like MeDiTATe?
As far as I know, this is one of the very first experiences of RINA in MSCA projects and, since the proposal stage, it was very challenging due to the large number of beneficiaries and partners involved. Large companies like RINA can definitively benefit from projects like MeDiTATe because, as it is a further opportunity to “virtuously contaminate each other” in terms of scientific knowledge and professional experience. Apart from that, we continue enjoying a longstanding collaboration with several of the players of the consortium.
How can the vision of a large company meet the scope of the MeDiTATe project?
In the end, one of the main objectives of MeDiTATe is to help ESRs in becoming high-profile professionals and scientists from whom the world community will benefit in the future. This is the same approach of the continuous improvement culture embraced by RINA to empower employees.
How do you think ESRs can benefit from the industrial approach that RINA proposes?
Together with the colleagues involved in MeDiTATe we have been trying to share first the RINA’s experience on communication and managerial topics creating, at least I hope, a positive environment to work in.
From a technical point of view, the presence and influence of private industrial entities like RINA are definitively an added value for ESRs. Our industrial-based thinking typically solicits ESRs to be more pragmatic in their daily work trying to ground their professional efforts in view of producing effective and exploitable solutions and applications. Read More
A new MeDiTATe project publication: A Hybrid Mock Circulatory Loop for Fluid Dynamic Characterization of 3D Anatomical Phantoms

Francesco Bardi, ESR 10 of the MeDiTATe project, published the paper titled A Hybrid Mock Circulatory Loop for Fluid Dynamic Characterization of 3D Anatomical Phantoms in the IEEE Transactions on Biomedical Engineering journal.
The work was developed in collaboration with Emanuele Gasparotti, Emanuele Vignali and Simona Celi from Bioengineering Unit (Fondazione Toscana G.Monasterio) and Stéphane Avril from Mines Saint-Étienne.
The paper, whose abstract is reported in the following lines, is available at this link.
This work presents the development of a Hybrid Mock Circulatory Loop (HMCL) to simulate hemodynamics at patient-specific level in terms of both 3D geometry and inlet/outlet boundary conditions. Methods: Clinical data have been processed to define the morphological and functional patient-specific settings. A piston pump is used to impose a parametric flow rate profile at the inlet of the hemodynamic circuit. In order to guarantee the physiological pressure and flow conditions, a specific hybrid chamber system including a real-time control has been designed and implemented. The developed system was validated firstly in a single outlet branch model and, secondly, on a 3D printed patient-specific multi-branch phantom. Finally, for the 3D phantom, the outlet flow profiles were compared with the corresponding in-vivo flow data. Results: Results showed that the root mean squared error between the prescribed setpoint and the measured pressures was always below 3 mmHg (about 2.5%) for all cases. The obtained flow profiles for the patient-specific model were in agreement with the related functional in-vivo data. Significance: The capability to reproduce physiological hemodynamics condition, with high-fidelity, plays a significant role in the cardiovascular research. The developed platform can be used to assess the performances of cardiovascular devices, to validate numerical simulations, and to test imaging systems.
Inauguration ceremony for CINECA’s Supercomputer LEONARDO

Last November 24th, the Inauguration Ceremony of CINECA‘s LEONARDO Pre-Exascale Supercomputer was held at Bologna Technopole, Italy.
LEONARDO, jointly funded by EuroHPC and CINECA (one of the MeDiTATe project partners) on behalf of the Italian Ministry of University and Research, has ranked 4th in the latest Top500 list of most powerful supercomputers in the world.
LEONARDO is one of the three pre-exascale systems of the EuroHPC Joint Undertaking (EuroHPC JU). The project is part of the actions that the European Union has been implementing to support the spread of High Performance Computing for research applications.
For more information on LEONARDO technical details visit Cineca’s dedicated page at this link.
Recent Posts
- The MeDiTATe project at the X International Conference on Computational Bioengineering (ICCB 2023)
- A new MeDiTATe project publication: “Enabling supra-aortic vessels inclusion in statistical shape models of the aorta: a novel non-rigid registration method”
- A new MeDiTATe project publication: “Prediction of guidewire-induced aortic deformations during EVAR: a finite element and in vitro study”
- Last week the MeDiTATe project was at the ESBiomech23
- A new MeDiTATe project publication: “Computer-aided shape features extraction and regression models for predicting the ascending aortic aneurysm growth rate”
Archives
- September 2023
- August 2023
- July 2023
- June 2023
- May 2023
- April 2023
- March 2023
- February 2023
- January 2023
- December 2022
- November 2022
- October 2022
- September 2022
- August 2022
- July 2022
- June 2022
- May 2022
- April 2022
- March 2022
- March 2021
- February 2021
- December 2020
- November 2020
- February 2020
- January 2020